SLC39A8 missense variant is associated with Crohn's disease but does not have a major impact on gut microbiome composition in healthy subjects.

<h4>Background</h4>Gene-microbiome interactions are important in aetiology and pathogenesis of inflammatory bowel disease, a chronic inflammatory disorder of the gastrointestinal tract consisting of Crohn's disease and ulcerative colitis. Scarce studies on gene-microbiome interactions show very litt...

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Detalhes bibliográficos

Principais autores:	Valerie Collij, Floris Imhann, Arnau Vich Vila, Jingyuan Fu, Gerard Dijkstra, Eleonora A M Festen, Michiel D Voskuil, Mark J Daly, Ramnik J Xavier, Cisca Wijmenga, Alexandra Zhernakova, Rinse K Weersma
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2019-01-01
coleção:	PLoS ONE
Acesso em linha:	https://doi.org/10.1371/journal.pone.0211328
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