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Tim4 enables large peritoneal macrophages to cross-present tumor antigens at early stages of tumorigenesis

Summary: Receptors controlling the cross-presentation of tumor antigens by macrophage subsets in cancer tissues are poorly explored. Here, we show that TIM4+ large peritoneal macrophages efficiently capture and cross-present tumor-associated antigens at early stages of peritoneal infiltration by ova...

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Principais autores: Sonal Joshi, Lucía López, Luciano Gastón Morosi, Roberto Amadio, Manendra Pachauri, Marco Bestagno, Ironya Paul Ogar, Mauro Giacca, Giulia Maria Piperno, Daan Vorselen, Federica Benvenuti
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-04-01
Serier:Cell Reports
Fag:
CP: Immunology
CP: Cancer
Online adgang:http://www.sciencedirect.com/science/article/pii/S2211124724004248
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