Tim4 enables large peritoneal macrophages to cross-present tumor antigens at early stages of tumorigenesis

Summary: Receptors controlling the cross-presentation of tumor antigens by macrophage subsets in cancer tissues are poorly explored. Here, we show that TIM4+ large peritoneal macrophages efficiently capture and cross-present tumor-associated antigens at early stages of peritoneal infiltration by ova...

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Detalhes bibliográficos

Principais autores:	Sonal Joshi, Lucía López, Luciano Gastón Morosi, Roberto Amadio, Manendra Pachauri, Marco Bestagno, Ironya Paul Ogar, Mauro Giacca, Giulia Maria Piperno, Daan Vorselen, Federica Benvenuti
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-04-01
Colecção:	Cell Reports
Assuntos:	CP: Immunology CP: Cancer
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124724004248
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