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Intercellular communication from myotubes to fibroblasts is differentially impacted by mineralocorticoid receptor signaling and muscular dystrophy

Abstract Background Replacement of striated muscle with fibrosis leads to the symptoms and fatality in Duchenne muscular dystrophy (DMD). Transient local production of the mineralocorticoid aldosterone in the skeletal muscle microenvironment enhances wound healing. However, persistent aldosterone si...

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Principais autores: Swathy Krishna, Chetan K. Gomatam, Reva Reddy, Jeovanna Lowe, Christoph Lepper, Jill A. Rafael-Fortney
格式: Artigo
語言:Inglês
出版: BMC 2025-11-01
叢編:Cell Communication and Signaling
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在線閱讀:https://doi.org/10.1186/s12964-025-02515-2
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