The exceptions that prove the rule—a historical view of bedaquiline susceptibility

Abstract In the accompanying study, Nimmo and colleagues estimated the dates of emergence of mutations in mmpR5 (Rv0678), the most important resistance gene to the anti-tuberculosis drug bedaquiline, in over 3500 geographically diverse Mycobacterium tuberculosis genomes. This provided important insi...

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Hlavní autoři:	Paolo Miotto, Daniela M. Cirillo, Thomas Schön, Claudio U. Köser
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-03-01
Edice:	Genome Medicine
Témata:	Mycobacterium tuberculosis Bedaquiline susceptibility Resistance mutations Clinical trials
On-line přístup:	https://doi.org/10.1186/s13073-024-01311-w
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