Machine learning approaches to detect hepatocyte chromatin alterations from iron oxide nanoparticle exposure

Abstract This study focuses on developing machine learning models to detect subtle alterations in hepatocyte chromatin organization due to Iron (II, III) oxide nanoparticle exposure, hypothesizing that exposure will significantly alter chromatin texture. A total of 2000 hepatocyte nuclear regions of...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Jovana Paunovic Pantic, Danijela Vucevic, Tatjana Radosavljevic, Peter R. Corridon, Svetlana Valjarevic, Jelena Cumic, Ljubisa Bojic, Igor Pantic
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2024-08-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Machine learning Nucleus Random forest Gradient boosting Toxicology
Online-Zugang:	https://doi.org/10.1038/s41598-024-70559-4
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!