ICOS+ T helper 2 cells promote the pulmonary fibrosis in systemic sclerosis

Abstract Background Interstitial lung disease (ILD) is the most frequent complication of systemic sclerosis (SSc), associated with a poor prognosis and limited treatments. T helper 2 (Th2) cells play a key role in SSc pathogenesis, with T cell inducible co-stimulator (ICOS) involved in Th2 different...

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Auteurs principaux:	Huimin Zhu, Yuxuan Chen, Yingyi Wu, Yue Zhang, Shanshan Liu, Na You, Mian Liu, Zhikang Wang, Dandan Wang, Lingyun Sun
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2026-03-01
Collection:	Molecular Medicine
Sujets:	Systemic sclerosis Interstitial lung disease T helper 2 cells IL-4
Accès en ligne:	https://doi.org/10.1186/s10020-026-01455-y
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