Tn Antigen Expression Contributes to an Immune Suppressive Microenvironment and Drives Tumor Growth in Colorectal Cancer

Expression of the tumor-associated glycan Tn antigen (αGalNAc-Ser/Thr) has been correlated to poor prognosis and metastasis in multiple cancer types. However, the exact mechanisms exerted by Tn antigen to support tumor growth are still lacking. One emerging hallmark of cancer is evasion of immune de...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Lenneke A. M. Cornelissen, Athanasios Blanas, Anouk Zaal, Joost C. van der Horst, Laura J. W. Kruijssen, Tom O’Toole, Yvette van Kooyk, Sandra J. van Vliet
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2020-08-01
Цуврал:	Frontiers in Oncology
Нөхцлүүд:	colorectal cancer O-glycosylation Tn antigen anti-tumor immunity tumor growth
Онлайн хандалт:	https://www.frontiersin.org/article/10.3389/fonc.2020.01622/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!