The synthesis, antimicrobial activity and docking studies of 6-(1H-benzimidazol-2-yl)-5-methylthieno[2,3-d]pyrimidin-4(3H)-ones with acetamide and 1,2,4-oxadiazol-5-ylmethyl substituents

Aim. To synthesize, study the antimicrobial activity and suggest antimicrobial activity mechanism for the novel derivatives of 6-(1H-benzimidazol-2-yl)-5-methylthieno[2,3-d]pyrimidin-4(3H)-one. Results and discussion. As the result of the targeted modification of 6-(1H-benzimidazol-2-yl)-5-methylth...

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Hlavní autoři:	Sergiy V. Vlasov, Oleksandr V. Borysov, Hanna I. Severina, Sergiy M. Kovalenko, Tetiana P. Osolodchenko, Vitaliy S. Vlasov, Victoriya A. Georgiyants
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National University of Pharmacy (Kharkiv) 2021-09-01
Edice:	Журнал органічної та фармацевтичної хімії
Témata:	thiophene pyrimidine alkylation antimicrobial agents inhibitors molecular docking
On-line přístup:	http://ophcj.nuph.edu.ua/article/view/240775
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