Elucidating the immune landscape and potential prognostic model in acute myeloid leukemia with TP53 mutation

Objectives The TP53 mutation, a prevalent tumor suppressor gene alteration, is linked to chemotherapy resistance, increased relapse rates and diminished overall survival (OS) in acute myeloid leukemia (AML) patients.Methods In this study, we characterize the TP53 mutation phenotypes across various A...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Gelan Zhu, Jiayi Cai, Wanbin Fu, Yue Sun, Ting Wang, Hua Zhong
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis Group 2024-12-01
Schriftenreihe:	Hematology
Schlagworte:	Prognostic model acute myeloid leukemia immune landscape TP53 mutation
Online-Zugang:	https://www.tandfonline.com/doi/10.1080/16078454.2024.2400620
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!