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Rationally Designing Aptamer Sequences with Reduced Affinity for Controlled Sensor Performance

The relative ease of predicting the secondary structure of nucleic acid sequences lends itself to the design of sequences to perform desired functions. Here, we combine the utility of nucleic acid aptamers with predictable control over the secondary structure to rationally design sequences with cont...

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Autors principals: Lauren R. Schoukroun-Barnes, Ryan J. White
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2015-03-01
Col·lecció:Sensors
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Accés en línia:http://www.mdpi.com/1424-8220/15/4/7754
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