Altered expression of 3α-hydroxysteroid dehydrogenases in human glaucomatous optic nerve head astrocytes
3α-Hydroxysteroid dehydrogenase (3α-HSD) isoforms (AKR1C1–AKR1C4) are aldo-keto reductases that metabolize steroids and other substances in many tissues including the CNS. Here we demonstrated that in glaucomatous human optic nerve heads, increased expression of 3α-HSD was localized to reactive astr...
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| Автори: | , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Elsevier
2003-10-01
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| Серія: | Neurobiology of Disease |
| Предмети: | |
| Онлайн доступ: | http://www.sciencedirect.com/science/article/pii/S0969996103001013 |
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