Diet-induced loss of adipose hexokinase 2 correlates with hyperglycemia

Chronically high blood glucose (hyperglycemia) leads to diabetes and fatty liver disease. Obesity is a major risk factor for hyperglycemia, but the underlying mechanism is unknown. Here, we show that a high-fat diet (HFD) in mice causes early loss of expression of the glycolytic enzyme Hexokinase 2...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Mitsugu Shimobayashi, Amandine Thomas, Sunil Shetty, Irina C Frei, Bettina K Wölnerhanssen, Diana Weissenberger, Anke Vandekeere, Mélanie Planque, Nikolaus Dietz, Danilo Ritz, Anne Christin Meyer-Gerspach, Timm Maier, Nissim Hay, Ralph Peterli, Sarah-Maria Fendt, Nicolas Rohner, Michael N Hall
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	eLife Sciences Publications Ltd 2023-03-01
سلاسل:	eLife
الموضوعات:	obesity glucose lipid metabolism adipose tissue diabetes selective insulin resistance
الوصول للمادة أونلاين:	https://elifesciences.org/articles/85103
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!