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Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions

Abstract The family of hexokinases (HKs) catalyzes the first step of glycolysis, the ATP-dependent phosphorylation of glucose to glucose-6-phosphate. While HK1 and HK2 are ubiquitously expressed, the less well-studied HK3 is primarily expressed in hematopoietic cells and tissues and is highly upregu...

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Bibliografische gegevens
Hoofdauteurs: Kristina Seiler, Magali Humbert, Petra Minder, Iris Mashimo, Anna M. Schläfli, Deborah Krauer, Elena A. Federzoni, Bich Vu, James J. Moresco, John R. Yates, Martin C. Sadowski, Ramin Radpour, Thomas Kaufmann, Jean-Emmanuel Sarry, Joern Dengjel, Mario P. Tschan, Bruce E. Torbett
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2022-05-01
Reeks:Cell Death and Disease
Online toegang:https://doi.org/10.1038/s41419-022-04891-w
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