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Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions

Abstract The family of hexokinases (HKs) catalyzes the first step of glycolysis, the ATP-dependent phosphorylation of glucose to glucose-6-phosphate. While HK1 and HK2 are ubiquitously expressed, the less well-studied HK3 is primarily expressed in hematopoietic cells and tissues and is highly upregu...

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Principais autores: Kristina Seiler, Magali Humbert, Petra Minder, Iris Mashimo, Anna M. Schläfli, Deborah Krauer, Elena A. Federzoni, Bich Vu, James J. Moresco, John R. Yates, Martin C. Sadowski, Ramin Radpour, Thomas Kaufmann, Jean-Emmanuel Sarry, Joern Dengjel, Mario P. Tschan, Bruce E. Torbett
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2022-05-01
סדרה:Cell Death and Disease
גישה מקוונת:https://doi.org/10.1038/s41419-022-04891-w
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