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The extended cleavage specificity of human thrombin.

Thrombin is one of the most extensively studied of all proteases. Its central role in the coagulation cascade as well as several other areas has been thoroughly documented. Despite this, its consensus cleavage site has never been determined in detail. Here we have determined its extended substrate r...

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Autores principales: Maike Gallwitz, Mattias Enoksson, Michael Thorpe, Lars Hellman
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2012-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC3288055?pdf=render
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