Glycosylated Ang-(1-7) MasR Agonist Peptide Poly Lactic-co-Glycolic Acid (PLGA) Nanoparticles and Microparticles in Cognitive Impairment: Design, Particle Preparation, Physicochemical Characterization, and In Vitro Release

Heart failure (HF) causes decreased brain perfusion in older adults, and increased brain and systemic inflammation increases the risk of cognitive impairment and Alzheimer’s disease (AD). Glycosylated Ang-(1-7) MasR agonists (PNA5) has shown improved bioavailability, stability, and brain penetration...

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Autores principales:	David Encinas-Basurto, John P. Konhilas, Robin Polt, Meredith Hay, Heidi M. Mansour
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2022-03-01
Colección:	Pharmaceutics
Materias:	PNA5 glycopeptide mas receptor angiotensin PLGA diblock copolymer ester and acid-end capped double emulsion solvent evaporation
Acceso en línea:	https://www.mdpi.com/1999-4923/14/3/587
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