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Folate receptor-targeted PEGylated PLGA nanoparticles for the site-specific delivery of hesperidin in epithelial ovarian cancer

Hesperidin (HSP) is a polyphenolic compound employed widely in the therapy of epithelial ovarian cancer (EOC). However, the low bioavailability, attributed to first-pass metabolism, low dissolution and poor tumour specificity, hampered its clinical effectiveness. Therefore, HSP-loaded folic acid-PEG...

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Principais autores: Rohini Kharwade, Nilesh M. Mahajan, Darshan R. Telange, Priyanka N. Yadav, Sachin R. More
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2026-12-01
Serier:Artificial Cells, Nanomedicine, and Biotechnology
Fag:
Hesperidin
PEGylated PLGA nanoparticles
folic acid
SKOV3 cell line
apoptosis
Online adgang:https://www.tandfonline.com/doi/10.1080/21691401.2026.2668273
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