The Histamine Pathway is a Target to Treat Hepatic Experimental Erythropoietic ProtoporphyriaSummary

Background & Aims: Erythropoietic protoporphyria (EPP) is caused by mutations in ferrochelatase, which inserts iron into protoporphyrin-IX (PP-IX) to generate heme. EPP is characterized by PP-IX accumulation, skin photosensitivity, cholestasis, and end-stage liver disease. Despite available drug...

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Detalhes bibliográficos

Principais autores:	Ning Kuo, Pei Li, Juliana Bragazzi Cunha, Lu Chen, Jordan A. Shavit, M. Bishr Omary
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-01-01
Colecção:	Cellular and Molecular Gastroenterology and Hepatology
Assuntos:	Anti-H1 Histamine Blocker Anti-H2 Histamine Blocker Ferrochelatase Porphyria-related Liver Disease
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2352345X25000049
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