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Simultaneous inhibition of aryl hydrocarbon receptor (AhR) and Src abolishes androgen receptor signaling.

Altered c-Src activity has been strongly implicated in the development, growth, progression, and metastasis of human cancers including prostate cancer. Src is known to regulate several biological functions of tumor cells, including proliferation. There are several Src inhibitors under evaluation for...

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Principais autores: Maryam Ghotbaddini, Keyana Cisse, Alexis Carey, Joann B Powell
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC5495210?pdf=render
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