SUMOylation of FOXP1 regulates transcriptional repression via CtBP1 to drive dendritic morphogenesis
Abstract Forkhead Box P (FOXP) transcriptional repressors play a major role in brain development and their dysfunction leads to human cognitive disorders. However, little is known about how the activity of these proteins is regulated. Here, we show that FOXP1 SUMOylation at lysine 670 is required fo...
Salvato in:
| Autori principali: | , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2017-04-01
|
| Serie: | Scientific Reports |
| Accesso online: | https://doi.org/10.1038/s41598-017-00707-6 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|