MTHFD2 marks pemetrexed resistance in pulmonary adenocarcinoma with EGFR wild type
Abstract Purpose Lung cancer is the leading cause of cancer-related deaths worldwide. Patients with an amplification of the MTHFD2 gene have a particularly poor prognosis. MTHFD2 signaling has been associated with migration, metastasis, and proliferation of lung cancer cells mediated through ERK sig...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Springer
2025-04-01
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| Серии: | Discover Oncology |
| Предметы: | |
| Online-ссылка: | https://doi.org/10.1007/s12672-025-02355-z |
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