Modification of RNF183 via m6A Methylation Mediates Podocyte Dysfunction in Diabetic Nephropathy by Regulating PKM2 Ubiquitination and Degradation

Diabetic kidney disease (DKD) is a prevalent complication associated with diabetes in which podocyte dysfunction significantly contributes to the development and progression of the condition. Ring finger protein 183 (RNF183) is an ER-localized, transmembrane ring finger protein with classical E3 lig...

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主要な著者:	Dongwei Guo, Yingxue Pang, Wenjie Wang, Yueying Feng, Luxuan Wang, Yuanyuan Sun, Jun Hao, Fan Li, Song Zhao
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2025-03-01
シリーズ:	Cells
主題:	diabetic kidney disease RNF183 m6A methylation ubiquitination PKM2
オンライン･アクセス:	https://www.mdpi.com/2073-4409/14/5/365
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