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The impact of congenital heart disease on the timing of Alzheimer's disease in Down syndrome

Abstract INTRODUCTION The incidence of Alzheimer's disease (AD) in Down syndrome (DS) exceeds 90%. Approximately 50% of people with DS have congenital heart disease (CHD). Having CHD increases risk for early‐onset AD in populations without DS, but it is unclear if CHD influences AD in DS. METHODS Da...

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Furkejuvvon:
Váldodahkkit: Julianne G. Clina, Brian C. Helsel, Sigan L. Hartley, David A. White, Victoria L. Fleming‐Batayneh, Benjamin Handen, Bradley Christian, Elizabeth Head, Mark Mapstone, Christy L. Hom, Beau Ances, Jeffrey Burns, H. Diana Rosas, Florence Lai, Sharon Krinsky McHale, Joseph H. Lee, Frederick A. Schmitt, Jordan Harp, Ira T. Lott, Shahid Zaman, Lauren T. Ptomey, for the Alzheimer Biomarker Consortium–Down Syndrome (ABC‐DS) Investigators
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Wiley 2026-01-01
Ráidu:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Fáttát:
Alzheimer's disease
cognition
congenital heart disease
dementia
Down syndrome
neuroimaging
Liŋkkat:https://doi.org/10.1002/dad2.70257
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