The impact of congenital heart disease on the timing of Alzheimer's disease in Down syndrome

Abstract INTRODUCTION The incidence of Alzheimer's disease (AD) in Down syndrome (DS) exceeds 90%. Approximately 50% of people with DS have congenital heart disease (CHD). Having CHD increases risk for early‐onset AD in populations without DS, but it is unclear if CHD influences AD in DS. METHODS Da...

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Detalles Bibliográficos

Principais autores:	Julianne G. Clina, Brian C. Helsel, Sigan L. Hartley, David A. White, Victoria L. Fleming‐Batayneh, Benjamin Handen, Bradley Christian, Elizabeth Head, Mark Mapstone, Christy L. Hom, Beau Ances, Jeffrey Burns, H. Diana Rosas, Florence Lai, Sharon Krinsky McHale, Joseph H. Lee, Frederick A. Schmitt, Jordan Harp, Ira T. Lott, Shahid Zaman, Lauren T. Ptomey, for the Alzheimer Biomarker Consortium–Down Syndrome (ABC‐DS) Investigators
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wiley 2026-01-01
Series:	Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Assuntos:	Alzheimer's disease cognition congenital heart disease dementia Down syndrome neuroimaging
Acceso en liña:	https://doi.org/10.1002/dad2.70257
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