Serum immune checkpoint profiling identifies soluble CD40 as a biomarker for pancreatic cancer

Abstract Pancreatic ductal adenocarcinoma (PDAC) responds poorly to systemic treatment, including new immunotherapeutic approaches. Biomarkers are urgently needed for early disease detection, patient stratification for treatment, and response prediction. The role of soluble CD40 (sCD40) is unknown i...

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Auteurs principaux:	David Digomann, Max Heiduk, Charlotte Reiche, Jessica Glück, Christoph Kahlert, Peter Mirtschink, Anna Klimova, Florian Bösch, Torsten Tonn, Jochen Gaedcke, Michael Ghadimi, Jürgen Weitz, Lena Seifert, Adrian M. Seifert
Format:	Artigo
Langue:	Inglês
Publié:	Nature Portfolio 2023-10-01
Collection:	npj Precision Oncology
Accès en ligne:	https://doi.org/10.1038/s41698-023-00459-9
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