Genetic analysis of single-minded 1 gene in early-onset severely obese children and adolescents.

<h4>Background</h4>Inactivating mutations of the hypothalamic transcription factor singleminded1 (SIM1) have been shown as a cause of early-onset severe obesity. However, to date, the contribution of SIM1 mutations to the obesity phenotype has only been studied in a few populations. In this study, w...

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Автори:	Daniela Stanikova, Marek Buzga, Patrik Krumpolec, Martina Skopkova, Martina Surova, Barbara Ukropcova, Lubica Ticha, Miroslava Petrasova, Dominika Gabcova, Miroslava Huckova, Lucie Piskorova, Jan Bozensky, Marian Mokan, Jozef Ukropec, Ivona Zavacka, Iwar Klimes, Juraj Stanik, Daniela Gasperikova
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Public Library of Science (PLoS) 2017-01-01
Серія:	PLoS ONE
Онлайн доступ:	https://doi.org/10.1371/journal.pone.0177222
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