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Multi-Omics Approach Reveals Dysregulation of Protein Phosphorylation Correlated with Lipid Metabolism in Mouse Non-Alcoholic Fatty Liver

Obesity caused by overnutrition is a major risk factor for non-alcoholic fatty liver disease (NAFLD). Several lipid intermediates such as fatty acids, glycerophospholipids and sphingolipids are implicated in NAFLD, but detailed characterization of lipids and their functional links to proteome and ph...

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Main Authors: Sora Q. Kim, Rodrigo Mohallem, Jackeline Franco, Kimberly K. Buhman, Kee-Hong Kim, Uma K. Aryal
Format: Artigo
Language:Inglês
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
NAFLD
fatty liver
HFD
mass spectrometry
proteomics
lipidomics
Online Access:https://www.mdpi.com/2073-4409/11/7/1172
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