DISCOVERIES OF GENE EDITING USING CRISPR-CAS9 FOR THE TREATMENT OF SICKLE CELL DISEASE: A LITERATURE REVIEW
Introduction/objectives: Sickle cell disease (SCD) is the most common monogenic blood disorder worldwide, causing reduced life expectancy to the patients. The innovative CRISPR-Cas9 gene-editing technology, pioneered by Jennifer Doudna and Emmanuelle Charpentier, has emerged as a potential curative...
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| Principais autores: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2024-10-01
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| coleção: | Hematology, Transfusion and Cell Therapy |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2531137924023253 |
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