A key role of the PGC-1α/ERR-α pathway in regulation of angiogenic factors in proliferative diabetic retinopathy

BackgroundPGC-1α is induced by hypoxia and interacts with the receptor ERR-α to stimulate angiogenic factors expression and promote angiogenesis. We investigated the possible role of the PGC-1α/ERR-α pathway in regulating angiogenic factors expression in proliferative diabetic retinopathy (PDR).Meth...

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מידע ביבליוגרפי

Principais autores:	Ahmed M. Abu El-Asrar, Mohd I. Nawaz, Ajmal Ahmad, Mairaj M. Siddiquei, Eef Allegaert, Priscilla W. Gikandi, Gert De Hertogh, Ghislain Opdenakker
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2025-07-01
סדרה:	Frontiers in Endocrinology
נושאים:	proliferative diabetic retinopathy angiogenesis PGC1-α ERR-α VEGF
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/fendo.2025.1615103/full
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