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Differential Expression and Localization of ADAMTS Proteinases in Proliferative Diabetic Retinopathy

We analyzed the expression of ADAMTS proteinases ADAMTS-1, -2, -4, -5 and -13; their activating enzyme MMP-15; and the degradation products of proteoglycan substrates versican and biglycan in an ocular microenvironment of proliferative diabetic retinopathy (PDR) patients. Vitreous samples from PDR a...

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Autores principales: Ahmed M. Abu El-Asrar, Mohd Imtiaz Nawaz, Eef Allegaert, Mohammad Mairaj Siddiquei, Ajmal Ahmad, Priscilla Gikandi, Gert De Hertogh, Ghislain Opdenakker
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2022-09-01
Colección:Molecules
Materias:
proliferative diabetic retinopathy
ADAMTS proteinases
MMP-15
versican
biglycan
Acceso en línea:https://www.mdpi.com/1420-3049/27/18/5977
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