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PCNA Ubiquitylation: Instructive or Permissive to DNA Damage Tolerance Pathways?

DNA lesions escaping from repair often block the DNA replicative polymerases required for DNA replication and are handled during the S/G2 phases by the DNA damage tolerance (DDT) mechanisms, which include the error-prone translesion synthesis (TLS) and the error-free template switching (TS) pathways...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Hauptverfasser: Jun Che, Xin Hong, Hai Rao
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2021-10-01
Schriftenreihe:Biomolecules
Schlagworte:
Online-Zugang:https://www.mdpi.com/2218-273X/11/10/1543
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