Quantification of plasma tau species containing the proline-rich region as a biomarker in Alzheimer’s disease

Abstract Tau-based blood biomarkers are increasingly recognised as important for the diagnosis of Alzheimer’s disease (AD). More than 60 proteolytic cleavage sites of tau have been identified, and current assays may miss critical information from some of the smaller protein fragments. By capturing a...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Mohammad Arastoo, Lewis K. Penny, Richard Lofthouse, Aaron Hitchcock, Anna Moelders, Sona Szalma, Andrew Porter, Soumya Palliyil, Charles R. Harrington, Claude M. Wischik
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Nature Portfolio 2025-11-01
Sarja:	Scientific Reports
Aiheet:	Alzheimer’s disease Tauopathy Tau protein Tau fragments Polyclonal antibody Biomarker
Linkit:	https://doi.org/10.1038/s41598-025-25864-x
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