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Selective Depletion of ZAP-Binding CpG Motifs in HCV Evolution

Hepatitis C virus (HCV) is a bloodborne pathogen that can cause chronic liver disease and hepatocellular carcinoma. The loss of CpGs from virus genomes allows escape from restriction by the host zinc-finger antiviral protein (ZAP). The evolution of HCV in the human host has not been explored in the...

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Principais autores: Sanket Mukherjee, Akhil Kumar, Jasmine Samal, Ekta Gupta, Perumal Vivekanandan, Manoj B. Menon
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-12-01
Serier:Pathogens
Fag:
HCV
CpG depletion
ZAP-binding motif
pathogenesis
evolution
HCV core gene
Online adgang:https://www.mdpi.com/2076-0817/12/1/43
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