Selective Depletion of ZAP-Binding CpG Motifs in HCV Evolution

Hepatitis C virus (HCV) is a bloodborne pathogen that can cause chronic liver disease and hepatocellular carcinoma. The loss of CpGs from virus genomes allows escape from restriction by the host zinc-finger antiviral protein (ZAP). The evolution of HCV in the human host has not been explored in the...

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Autores principales:	Sanket Mukherjee, Akhil Kumar, Jasmine Samal, Ekta Gupta, Perumal Vivekanandan, Manoj B. Menon
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2022-12-01
Colección:	Pathogens
Materias:	HCV CpG depletion ZAP-binding motif pathogenesis evolution HCV core gene
Acceso en línea:	https://www.mdpi.com/2076-0817/12/1/43
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