In renal cell carcinoma the PTEN splice variant PTEN-Δ shows similar function as the tumor suppressor PTEN itself

Abstract Background Loss of PTEN is involved in tumor progression of several tumor entities including renal cell carcinoma (RCC). During the translation process PTEN generates a number of splice variants, including PTEN-Δ. We analyzed the impact of PTEN-Δ in RCC progression. Methods In specimens of...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Ines Breuksch, Jonas Welter, Heide-Katharina Bauer, Thorsten Enklaar, Sebastian Frees, Joachim W. Thüroff, Annette Hasenburg, Dirk Prawitt, Walburgis Brenner
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2018-06-01
Rangatū:	Cell Communication and Signaling
Ngā marau:	PTEN Renal cell carcinoma Splice variant PTEN-Δ Tumor progression Metastasis
Urunga tuihono:	http://link.springer.com/article/10.1186/s12964-018-0247-9
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!