Brain vascular stability relies on PAK2–cilia–PDGF-BB–HSPGs on basolateral side of endothelium

This study identifies a unique cellular mechanism involving basolateral endothelial cilia, platelet-derived growth factor-BB, and heparan sulfate proteoglycans that helps explain vascular stability in vertebrates. Endothelial cells (ECs) in the brain communicate with mural cells to facilitate vascul...

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Bibliografiske detaljer

Principais autores:	Shubhangi Prabhudesai, Karthikeyan Thirugnanam, Xuehong Song, Hua Yang, Mariella Errede, Francesco Girolamo, Thomas Neumann, Andrea Marzullo, Sepand Bafti, Kayla Vanderhoef, Kevin R Rarick, Andrew D Spearman, Amy Y Pan, Claudia Alvarez Alvarez, Jiyuan Yang, Fuming Zhang, Jonathan S Dordick, Daniela Virgintino, Lianchun Wang, Ramani Ramchandran
Format:	Artigo
Sprog:	Inglês
Udgivet:	Life Science Alliance LLC 2026-03-01
Serier:	Life Science Alliance
Online adgang:	https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202503460
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