Glymphatic influx and clearance are perturbed in Huntington’s disease

The accumulation of mutant huntingtin protein aggregates in neurons is a pathological hallmark of Huntington’s disease (HD). The glymphatic system, a brain-wide perivascular network, facilitates the exchange of interstitial fluid and cerebrospinal fluid (CSF), supporting interstitial solute clearanc...

Descripció completa

Dades bibliogràfiques

Autors principals:	Hongshuai Liu, Lin Chen, Chuangchuang Zhang, Chang Liu, Yuguo Li, Liam Cheng, Yuxiao Ouyang, Catherine Rutledge, John Anderson, Zhiliang Wei, Ziqin Zhang, Hanzhang Lu, Peter C.M. van Zijl, Jeffrey J. Iliff, Jiadi Xu, Wenzhen Duan
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Clinical investigation 2024-10-01
Col·lecció:	JCI Insight
Matèries:	Neuroscience
Accés en línia:	https://doi.org/10.1172/jci.insight.172286
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!