QR Kod

Identification and Validation of VEGFR2 Kinase as a Target of Voacangine by a Systematic Combination of DARTS and MSI

Although natural products are an important source of drugs and drug leads, identification and validation of their target proteins have proven difficult. Here, we report the development of a systematic strategy for target identification and validation employing drug affinity responsive target stabili...

Ful tanımlama

Kaydedildi:
Asıl Yazarlar: Yonghyo Kim, Yutaka Sugihara, Tae Young Kim, Sung Min Cho, Jin Young Kim, Ju Yeon Lee, Jong Shin Yoo, Doona Song, Gyoonhee Han, Melinda Rezeli, Charlotte Welinder, Roger Appelqvist, György Marko-Varga, Ho Jeong Kwon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2020-03-01
Seri Bilgileri:Biomolecules
Konular:
target identification
target validation
label-free method for drugs
anti-angiogenesis
mechanism of action
receptor tyrosine kinases
Online Erişim:https://www.mdpi.com/2218-273X/10/4/508
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller