Toxicological Screening of Four Bioactive Citroflavonoids: In Vitro, In Vivo, and In Silico Approaches

Many studies describe different pharmacological effects of flavonoids on experimental animals and humans. Nevertheless, few ones are confirming the safety of these compounds for therapeutic purposes. This study aimed to investigate the preclinical safety of naringenin, naringin, hesperidin, and quer...

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Main Authors:	Rolffy Ortiz-Andrade, Jesús Alfredo Araujo-León, Amanda Sánchez-Recillas, Gabriel Navarrete-Vazquez, Avel Adolfo González-Sánchez, Sergio Hidalgo-Figueroa, Ángel Josabad Alonso-Castro, Irma Aranda-González, Emanuel Hernández-Núñez, Tania Isolina Coral-Martínez, Juan Carlos Sánchez-Salgado, Victor Yáñez-Pérez, M. A. Lucio-Garcia
Format:	Artigo
Language:	Inglês
Published:	MDPI AG 2020-12-01
Series:	Molecules
Subjects:	citroflavonoids low-risk substances acute oral toxicity MTT-based assay toxicity prediction
Online Access:	https://www.mdpi.com/1420-3049/25/24/5959
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