Design of Poly(lactic-<i>co</i>-glycolic Acid) (PLGA) Nanoparticles for Vaginal Co-Delivery of Griffithsin and Dapivirine and Their Synergistic Effect for HIV Prophylaxis

Long-acting topical products for pre-exposure prophylaxis (PrEP) that combine antiretrovirals (ARVs) inhibiting initial stages of infection are highly promising for prevention of HIV sexual transmission. We fabricated core-shell poly(lactide-<i>co</i>-glycolide) (PLGA) nanoparticles, loaded with two...

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Detalhes bibliográficos

Principais autores:	Haitao Yang, Jing Li, Sravan Kumar Patel, Kenneth E. Palmer, Brid Devlin, Lisa C. Rohan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2019-04-01
coleção:	Pharmaceutics
Assuntos:	microbicides HIV combination ARVs sustained release synergism PLGA nanoparticles co-delivery
Acesso em linha:	https://www.mdpi.com/1999-4923/11/4/184
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