Serine Palmitoyltransferase Gene Silencing Prevents Ceramide Accumulation and Insulin Resistance in Muscles in Mice Fed a High-Fat Diet

Skeletal muscles account for ~80% of insulin-stimulated glucose uptake and play a key role in lipid metabolism. Consumption of a high-fat diet (HFD) contributes to metabolic changes in muscles, including the development of insulin resistance. The studies carried out to date indicate that the accumul...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Monika Imierska, Piotr Zabielski, Kamila Roszczyc-Owsiejczuk, Emilia Sokołowska, Karolina Pogodzińska, Iwona Kojta, Agnieszka Błachnio-Zabielska
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2022-03-01
Цуврал:	Cells
Нөхцлүүд:	insulin resistance ceramide skeletal muscle lipid metabolism gene silencing electroporation
Онлайн хандалт:	https://www.mdpi.com/2073-4409/11/7/1123
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!