ABCB1 and ABCG2 restricts the efficacy of gedatolisib (PF-05212384), a PI3K inhibitor in colorectal cancer cells
Abstract Background Overexpression of ABC transporters is a big challenge on cancer therapy which will lead cancer cells resistance to a series of anticancer drugs. Gedatolisib is a dual PI3K and mTOR inhibitor which is under clinical evaluation for multiple types of malignancies, including colorect...
Na minha lista:
| Principais autores: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2021-02-01
|
| coleção: | Cancer Cell International |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s12935-021-01800-7 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|