M402, a novel heparan sulfate mimetic, targets multiple pathways implicated in tumor progression and metastasis.

Heparan sulfate proteoglycans (HSPGs) play a key role in shaping the tumor microenvironment by presenting growth factors, cytokines, and other soluble factors that are critical for host cell recruitment and activation, as well as promoting tumor progression, metastasis, and survival. M402 is a ratio...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	He Zhou, Sucharita Roy, Edward Cochran, Radouane Zouaoui, Chia Lin Chu, Jay Duffner, Ganlin Zhao, Sean Smith, Zoya Galcheva-Gargova, Juliane Karlgren, Nancy Dussault, Rain Y Q Kwan, Erick Moy, Marishka Barnes, Alison Long, Chris Honan, Yi Wei Qi, Zachary Shriver, Tanmoy Ganguly, Birgit Schultes, Ganesh Venkataraman, Takashi Kei Kishimoto
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Public Library of Science (PLoS) 2011-01-01
سلاسل:	PLoS ONE
الوصول للمادة أونلاين:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0021106&type=printable
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!