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Characterisation of the interaction of neuropilin-1 with heparin and a heparan sulfate mimetic library of heparin-derived sugars

Background. Neuropilin-1 (NRP-1) is a multidomain membrane protein with soluble isoforms interacting with a complex network of other membrane receptors, their respective ligands and heparan sulfate (HS). It is involved in the development of vasculature, neural patterning, immunological responses and...

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Autors principals: Katarzyna A. Uniewicz, Alessandro Ori, Yassir A. Ahmed, Edwin A. Yates, David G. Fernig
Format: Artigo
Idioma:Inglês
Publicat: PeerJ Inc. 2014-06-01
Col·lecció:PeerJ
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Accés en línia:https://peerj.com/articles/461.pdf
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