Human colonic EVs induce murine enteric neuroplasticity via the lncRNA GAS5/miR-23/NMDA NR2B axis

Postinfectious, diarrhea-predominant, irritable bowel syndrome (PI-IBS-D) is difficult to treat owing to its unknown pathophysiology. Extracellular vesicles (EVs) derived from human colon tissue and long noncoding RNAs (lncRNAs), such as growth arrest–specific 5 (GAS5), may play key roles in the pat...

Descrición completa

Detalles Bibliográficos

Principais autores:	QiQi Zhou, Liuqing Yang, Zachary T. Verne, Benjamin B. Zhang, Jeremy Z. Fields, Amber T. Thacker, G. Nicholas Verne
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical investigation 2025-03-01
Series:	JCI Insight
Assuntos:	Gastroenterology
Acceso en liña:	https://doi.org/10.1172/jci.insight.178631
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!