Natural Coumarin Derivative Esculetin Regulates Platelet Activation via Modulating NF-κB Signaling in Cyclic Nucleotide-Independent Manner

Esculetin, a natural coumarin derivative, shows exciting biological activities in a variety of cell and animal models. Our recent study demonstrated that esculetin exhibits antiplatelet effects by obstructing the phospholipase C γ2/protein kinase C cascade, hydroxyl radical formation, and Akt activa...

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Hlavní autoři:	Chih-Wei Hsia, Kou-Gi Shyu, Thanasekaran Jayakumar, Chih-Hsuan Hsia, Marappan Velusamy, Chih-Hao Yang, Joen-Rong Sheu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	SAGE Publishing 2019-12-01
Edice:	Natural Product Communications
On-line přístup:	https://doi.org/10.1177/1934578X19896663
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