Decreased Human Platelet Activation and Mouse Pulmonary Thrombosis by Rutaecarpine and Comparison of the Relative Effectiveness with BAY11-7082: Crucial Signals of p38-NF-κB

Platelets play a critical role in arterial thrombosis. Rutaecarpine (RUT) was purified from <i>Tetradium ruticarpum</i>, a well-known Chinese medicine. This study examined the relative activity of RUT with NF-κB inhibitors in human platelets. BAY11-7082 (an inhibitor of IκB kinase [IKK]), Ro106-9920...

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Bibliografske podrobnosti

Principais autores:	Wei-Chieh Huang, Shaw-Min Hou, Ming-Ping Wu, Chih-Wei Hsia, Thanasekaran Jayakumar, Chih-Hsuan Hsia, Periyakali Saravana Bhavan, Chi-Li Chung, Joen-Rong Sheu
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2022-01-01
Serija:	Molecules
Teme:	DPPH human platelets p38 MAPK NF-κB pulmonary thrombosis rutaecarpine
Online dostop:	https://www.mdpi.com/1420-3049/27/2/476
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