Association of TRAIL receptor with phosphatase SHP-1 enables repressing T cell receptor signaling and T cell activation through inactivating Lck

Abstract Background T cell receptor (TCR) signaling and T cell activation are tightly regulated by gatekeepers to maintain immune tolerance and avoid autoimmunity. The TRAIL receptor (TRAIL-R) is a TNF-family death receptor that transduces apoptotic signals to induce cell death. Recent studies have...

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Autori principali:	I-Tsu Chyuan, Hsiu-Jung Liao, Tse-Hua Tan, Huai-Chia Chuang, Yu-Chuan Chu, Meng-Hsun Pan, Chien-Sheng Wu, Ching-Liang Chu, Bor-Ching Sheu, Ping-Ning Hsu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2024-03-01
Serie:	Journal of Biomedical Science
Soggetti:	TRAIL receptor Phosphatase SHP-1 T cell receptor signaling
Accesso online:	https://doi.org/10.1186/s12929-024-01023-8
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