Integrative metabolomic and single-cell transcriptomic analysis of recurrent condyloma acuminatum in humans

Abstract Condyloma acuminatum (CA), primarily caused by low-risk HPV6/11, is a benign proliferative disease that is difficult to cure and prone to recurrence. However, the molecular and immune mechanisms underlying relapse remain unclear. We combined metabolomic profiling with single-cell RNA sequen...

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Główni autorzy:	Yushu Wei, Yaohan Xu, Chenxi Feng, Siji Chen, Jie Chen, Jiacheng Wang, Jingying Pan, Yinjing Song, Chunting Hua, Miaolian Cai, Hao Cheng, Jiang Zhu
Format:	Artigo
Język:	Inglês
Wydane:	Nature Portfolio 2026-02-01
Seria:	Scientific Reports
Hasła przedmiotowe:	Condyloma acuminatum Human papillomavirus Recurrence Metabolomics Single-cell sequencing Immunometabolism
Dostęp online:	https://doi.org/10.1038/s41598-026-37989-8
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